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Molecule List for Accession CaMKII (Accession Number33) | Default ordering is done according to Pathway Number. Table headers can be used for changing the default ordering.
  arrow indicates that ordering is done according to ascending or descending order.
The entries are grouped according to Pathway Number and are alternately color coded using  and  color. |
| |
Name | Pathway Name /
Pathway No. | Accession
Type | Initial
Conc.
(uM) | Volume
(fL) | Buffered | Sum Total Of | | 1 | Total_CaMKII | CaMKII
Pathway No. 174 | Network | 127.325 | 0.1309 | No | - | | | This is not directly in the Holmes model. It is a trick used in GENESIS/Kinetikit to scale activity down for intramolecular reactions. Here it is used to scale the autophosph reactions such that only neighboring subunits will phosphorylate each other. This is done by scaling down the actual conc (in the enzyme parent, Tot-active-CaMKII) by the total conc such that instead of a conc, we the fraction of nearby subunits that will be active. Note that this conc of 10000 CaMKII subunits is 10 times the true conc, since only 1/10 of the molecules are neighboring molecules. | | 2 | CaM | CaM
Pathway No. 173 | Network | 79.9997 | 0.1309 | No | - | | | Init conc form model is 80 uM. | | 3 | CaMKII | CaMKII
Pathway No. 174 | Network | 12.7325 | 0.1309 | No | - | | | Init level is 100 holoenzymes of 10 subunits each. | | 4 | CaN | CaN
Pathway No. 175 | Network | 3.6415 | 0.1309 | No | - | | | Holmes assumes that there are 286 calcinuerin molecules. | | 5 | Ca | Shared_Object_
CaMKII
Pathway No. 172Network | 0.07 | 0.1309 | No | - | | | | 70 nM initial conc from Holmes. | | 6 | CAMKII-CaMCa | CaMKII
Pathway No. 174 | Network | 0 | 0.1309 | No | - | | 7 | CaMKII-CaMCa2 | CaMKII
Pathway No. 174 | Network | 0 | 0.1309 | No | - | | 8 | CaMKII-CaMCa3 | CaMKII
Pathway No. 174 | Network | 0 | 0.1309 | No | - | | 9 | CaMKII-CaMCa4 | CaMKII
Pathway No. 174 | Network | 0 | 0.1309 | No | - | | 10 | CaMCa | CaM
Pathway No. 173 | Network | 0 | 0.1309 | No | - | | 11 | CaMCa2 | CaM
Pathway No. 173 | Network | 0 | 0.1309 | No | - | | 12 | CaMCa3 | CaM
Pathway No. 173 | Network | 0 | 0.1309 | No | - | | 13 | CaMCa4 | CaM
Pathway No. 173 | Network | 0 | 0.1309 | No | - | | 14 | CaMKII-CaM | CaMKII
Pathway No. 174 | Network | 0 | 0.1309 | No | - | | 15 | Trapped-T286 | CaMKII
Pathway No. 174 | Network | 0 | 0.1309 | No | - | | 16 | Capped | CaMKII
Pathway No. 174 | Network | 0 | 0.1309 | No | - | | 17 | Autonomous | CaMKII
Pathway No. 174 | Network | 0 | 0.1309 | No | - | | 18 | CaN-CaM | CaN
Pathway No. 175 | Network | 0 | 0.1309 | No | - | | 19 | CaN-CaMCa | CaN
Pathway No. 175 | Network | 0 | 0.1309 | No | - | | 20 | CaN-CaMCa2 | CaN
Pathway No. 175 | Network | 0 | 0.1309 | No | - |
| Database compilation and code copyright (C) 2022, Upinder S. Bhalla and NCBS/TIFR
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